Charleston is known for award-winning hotels, grand antebellum mansions, and prominent cuisine, but take the tykes with you to this Southern gem and you’ll see the destination from a completely new perspective. First stop: visit the wharf where English settlers landed in 1670 at Charles Towne Landing. The 80-acre state park explores what life was like at the time of settlement with a reproduction period sailing vessel, a garden that recreates the first harvest, and a natural habitat zoo populated by indigenous animals. At the South Carolina Aquarium, families can take a behind-the-scenes tour of the Sea Turtle Hospital to learn how compassionate staff members are nursing the turtles back to healthy lives. Next stop: the Children’s Museum of the Lowcountry, where the little ones can climb to the top of a medieval castle, take the helm of a Lowcountry pirate ship, or create a masterpiece in the museum’s Art Center. More of our favorite family-friendly locales include Blue Bicycle Books, Charleston Pirate Tours, the North Charleston Fire Museum & Educational Center, Patriots Point Naval & Maritime Museum, Splash Island Waterpark, The Alley, and Whirlin’ Waters Adventure Waterpark.